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Chromatin Organization Measured by AluI Restriction Enzyme Changes with Malignancy and Is Regulated by the Extracellular Matrix and the Cytoskeleton

Given that expression of many genes changes when cells become malignant or are placed in different microenvironments, we asked whether these changes were accompanied by global reorganization of chromatin. We reasoned that sequestration or exposure of chromatin-sensitive sites to restriction enzymes...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Maniotis, Andrew J., Valyi-Nagy, Klara, Karavitis, John, Moses, Jonas, Boddipali, Viveka, Wang, Ying, Nuñez, Rafael, Setty, Suman, Arbieva, Zarema, Bissell, Mina J., Folberg, Robert
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602386/
https://ncbi.nlm.nih.gov/pubmed/15793298
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