Tumor Cell Plasticity in Uveal Melanoma : Microenvironment Directed Dampening of the Invasive and Metastatic Genotype and Phenotype Accompanies the Generation of Vasculogenic Mimicry Patterns

The histological detection of laminin-rich vasculogenic mimicry patterns in human primary uveal melanomas is associated with death from metastases. We therefore hypothesized that highly invasive uveal melanoma cells forming vasculogenic mimicry patterns after exposure to a laminin-rich three-dimensi...

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Hlavní autoři: Folberg, Robert, Arbieva, Zarema, Moses, Jonas, Hayee, Amin, Sandal, Tone, Kadkol, ShriHari, Lin, Amy Y., Valyi-Nagy, Klara, Setty, Suman, Leach, Lu, Chévez-Barrios, Patricia, Larsen, Peter, Majumdar, Dibyen, Pe’er, Jacob, Maniotis, Andrew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698855/
https://ncbi.nlm.nih.gov/pubmed/17003493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060223
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