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Epigenetic Reversion of Breast Carcinoma Phenotype Is Accompanied by Changes in DNA Sequestration as Measured by AluI Restriction Enzyme

The importance of microenvironment and context in regulation of tissue-specific genes is well established. DNA exposure to or the sequestration from nucleases detects differences in higher order chromatin structure in intact cells without disturbing cellular or tissue architecture. To investigate th...

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Autors principals: Sandal, Tone, Valyi-Nagy, Klara, Spencer, Virginia A., Folberg, Robert, Bissell, Mina J., Maniotis, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854967/
https://ncbi.nlm.nih.gov/pubmed/17456778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060922
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