Chromatin Organization Measured by AluI Restriction Enzyme Changes with Malignancy and Is Regulated by the Extracellular Matrix and the Cytoskeleton

Given that expression of many genes changes when cells become malignant or are placed in different microenvironments, we asked whether these changes were accompanied by global reorganization of chromatin. We reasoned that sequestration or exposure of chromatin-sensitive sites to restriction enzymes...

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Détails bibliographiques
Auteurs principaux: Maniotis, Andrew J., Valyi-Nagy, Klara, Karavitis, John, Moses, Jonas, Boddipali, Viveka, Wang, Ying, Nuñez, Rafael, Setty, Suman, Arbieva, Zarema, Bissell, Mina J., Folberg, Robert
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2005
Sujets:
Original Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602386/
https://ncbi.nlm.nih.gov/pubmed/15793298
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