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Up-Regulation of the Redox Mediators Thioredoxin and Apurinic/Apyrimidinic Excision (APE)/Ref-1 in Hypoxic Microregions of Invasive Cervical Carcinomas, Mapped Using Multispectral, Wide-Field Fluorescence Image Analysis

Thioredoxin and apurinic/apyrimidinic excision (APE)/ref-1 are important redox mediators in biochemical pathways that promote cell survival under adverse conditions including hypoxia and oxidative stress. For example, elevated levels occur surrounding vascular infarcts and protect from reperfusion i...

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Главные авторы: Hedley, David, Pintilie, Melania, Woo, Jennifer, Nicklee, Trudey, Morrison, Andrew, Birle, Diana, Fyles, Anthony, Milosevic, Michael, Hill, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602260/
https://ncbi.nlm.nih.gov/pubmed/14742261
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