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Up-Regulation of the Redox Mediators Thioredoxin and Apurinic/Apyrimidinic Excision (APE)/Ref-1 in Hypoxic Microregions of Invasive Cervical Carcinomas, Mapped Using Multispectral, Wide-Field Fluorescence Image Analysis

Thioredoxin and apurinic/apyrimidinic excision (APE)/ref-1 are important redox mediators in biochemical pathways that promote cell survival under adverse conditions including hypoxia and oxidative stress. For example, elevated levels occur surrounding vascular infarcts and protect from reperfusion i...

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Detalhes bibliográficos
Main Authors: Hedley, David, Pintilie, Melania, Woo, Jennifer, Nicklee, Trudey, Morrison, Andrew, Birle, Diana, Fyles, Anthony, Milosevic, Michael, Hill, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602260/
https://ncbi.nlm.nih.gov/pubmed/14742261
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