The molecular basis for T-type Ca(2+) channel inhibition by G protein β(2)γ(2) subunits

Gβγ, a ubiquitous second messenger, relays external signals from G protein-coupled receptors to networks of intracellular effectors, including voltage-dependent calcium channels. Unlike high-voltage-activated Ca(2+) channels, the inhibition of low-voltage-activated Ca(2+) channels is subtype-depende...

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Bibliografiska uppgifter
Huvudupphovsmän: DePuy, Seth D., Yao, Junlan, Hu, Changlong, McIntire, William, Bidaud, Isabelle, Lory, Philippe, Rastinejad, Fraydoon, Gonzalez, Carlos, Garrison, James C., Barrett, Paula Q.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1600004/
https://ncbi.nlm.nih.gov/pubmed/16973746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603945103
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