Molecular basis for the modulation of native T-type Ca(2+) channels in vivo by Ca(2+) /calmodulin-dependent protein kinase II

Ang II receptor activation increases cytosolic Ca(2+) levels to enhance the synthesis and secretion of aldosterone, a recently identified early pathogenic stimulus that adversely influences cardiovascular homeostasis. Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a downstream effector of...

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Detalhes bibliográficos
Main Authors: Yao, Junlan, Davies, Lucinda A., Howard, Jason D., Adney, Scott K., Welsby, Philip J., Howell, Nancy, Carey, Robert M., Colbran, Roger J., Barrett, Paula Q.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550277/
https://ncbi.nlm.nih.gov/pubmed/16917542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27918
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