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Postexposure vaccination massively increases the prevalence of γ-herpesvirus-specific CD8(+) T cells but confers minimal survival advantage on CD4-deficient mice
Mice that lack CD4(+) T cells remain clinically normal for more than 60 days after respiratory challenge with the murine γ-herpesvirus 68 (γHV-68), then develop symptoms of a progressive wasting disease. The γHV-68-specific CD8(+) T cells that persist in these I-A(b−/−) mice are unable to prevent co...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The National Academy of Sciences
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15997/ https://ncbi.nlm.nih.gov/pubmed/10694575 |
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