Postexposure vaccination massively increases the prevalence of γ-herpesvirus-specific CD8(+) T cells but confers minimal survival advantage on CD4-deficient mice
Mice that lack CD4(+) T cells remain clinically normal for more than 60 days after respiratory challenge with the murine γ-herpesvirus 68 (γHV-68), then develop symptoms of a progressive wasting disease. The γHV-68-specific CD8(+) T cells that persist in these I-A(b−/−) mice are unable to prevent co...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10694575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040575197 |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
