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Zinc transfer potentials of the α- and β-clusters of metallothionein are affected by domain interactions in the whole molecule

The α- and β-polypeptides of human metallothionein (isoform 2), obtained by chemical synthesis, were converted into their respective zinc/thiolate clusters, and each domain was investigated separately. Proton titration data for the N-terminal β-domain fit a simple model with three ionizations of the...

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Autors principals: Jiang, Li-Juan, Vašák, Milan, Vallee, Bert L., Maret, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15958/
https://ncbi.nlm.nih.gov/pubmed/10716985
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