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Inhibitory sites in enzymes: Zinc removal and reactivation by thionein

Thionein (T) has not been isolated previously from biological material. However, it is generated transiently in situ by removal of zinc from metallothionein under oxidoreductive conditions, particularly in the presence of selenium compounds. T very rapidly activates a group of enzymes in which zinc...

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Detalhes bibliográficos
Main Authors: Maret, Wolfgang, Jacob, Claus, Vallee, Bert L., Fischer, Edmond H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26715/
https://ncbi.nlm.nih.gov/pubmed/10051573
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