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Zinc transfer potentials of the α- and β-clusters of metallothionein are affected by domain interactions in the whole molecule
The α- and β-polypeptides of human metallothionein (isoform 2), obtained by chemical synthesis, were converted into their respective zinc/thiolate clusters, and each domain was investigated separately. Proton titration data for the N-terminal β-domain fit a simple model with three ionizations of the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15958/ https://ncbi.nlm.nih.gov/pubmed/10716985 |
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