Deactivation of phosphatidylinositol 3,4,5-trisphosphate/Akt signaling mediates neutrophil spontaneous death

Neutrophil spontaneous death plays essential roles in neutrophil homeostasis and resolution of inflammation, whereas the underlying molecular mechanisms are still ill-defined. Neutrophils die because of programmed cell death or apoptosis. However, treatment with inhibitor of caspases, which are resp...

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Daocheng, Hattori, Hidenori, Jo, Hakryul, Jia, Yonghui, Subramanian, Kulandayan K., Loison, Fabien, You, Jian, Le, Yi, Honczarenko, Marek, Silberstein, Leslie, Luo, Hongbo R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1595438/
https://ncbi.nlm.nih.gov/pubmed/16988010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605722103
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