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Role of Intrachain Disulfides in the Activities of the CdtA and CdtC Subunits of the Cytolethal Distending Toxin of Actinobacillus actinomycetemcomitans

The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans is an atypical A-B-type toxin consisting of a heterotrimer composed of the cdtA, cdtB, and cdtC gene products. The CdtA and CdtC subunits form two heterogeneous ricin-like lectin domains which bind the holotoxin to the tar...

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Main Authors: Cao, Linsen, Volgina, Alla, Korostoff, Jonathan, DiRienzo, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594843/
https://ncbi.nlm.nih.gov/pubmed/16926390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00697-06
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