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Characterization of point mutations in the cdtA gene of the cytolethal distending toxin of Actinobacillus actinomycetemcomitans

The Cdt is a family of gram-negative bacterial toxins that typically arrest eukaryotic cells in the G(0)/G(1) or G2/M phase of the cell cycle. The toxin is a heterotrimer composed of the cdtA, cdtB and cdtC gene products. Although it has been shown that the CdtA protein subunit binds to cells in cul...

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Detalhes bibliográficos
Main Authors: Cao, Linsen, Volgina, Alla, Huang, Chuang-ming, Korostoff, Jonathan, DiRienzo, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435350/
https://ncbi.nlm.nih.gov/pubmed/16313618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2005.04905.x
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