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Functional Analysis of p53 Binding under Differential Stresses

Hypoxia and DNA damage stabilize the p53 protein, but the subsequent effect that each stress has on transcriptional regulation of known p53 target genes is variable. We have used chromatin immunoprecipitation followed by CpG island (CGI) microarray hybridization to identify promoters bound by p53 un...

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Detalhes bibliográficos
Main Authors: Krieg, Adam J., Hammond, Ester M., Giaccia, Amato J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592883/
https://ncbi.nlm.nih.gov/pubmed/16980608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00322-06
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