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Hematopoietic Precursor Cells Transiently Reestablish Permissiveness for X Inactivation

Xist is the trigger for X inactivation in female mammals. The long noncoding Xist RNA localizes along one of the two female X chromosomes and initiates chromosome-wide silencing in the early embryo. In differentiated cells, Xist becomes dispensable for the maintenance of the inactive X, and its func...

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Autori principali: Savarese, Fabio, Flahndorfer, Katja, Jaenisch, Rudolf, Busslinger, Meinrad, Wutz, Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592878/
https://ncbi.nlm.nih.gov/pubmed/16980619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00810-06
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