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CD6 Regulates T-Cell Responses through Activation-Dependent Recruitment of the Positive Regulator SLP-76
Deciphering the role of lymphocyte membrane proteins depends on dissecting the role of a protein in the steady state and on engagement with its ligand. We show that expression of CD6 in T cells limits their responsiveness but that engagement by the physiological ligand CD166 gives costimulation. Thi...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592849/ https://ncbi.nlm.nih.gov/pubmed/16914752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00688-06 |
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