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T Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex
The cell surface receptor CD6 regulates T cell activation in both activating and inhibitory manners. The adaptor protein SLP-76 is recruited to the phosphorylated CD6 cytoplasmic Y662 residue during T cell activation, providing an activating signal to T cells. In this study, a biochemical approach i...
Bewaard in:
| Gepubliceerd in: | Mol Cell Biol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5440646/ https://ncbi.nlm.nih.gov/pubmed/28289074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00071-17 |
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