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Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

Hedgehog (HH)/GLI signaling plays a critical role in epidermal development and basal cell carcinoma. Here, we provide evidence that epidermal growth factor receptor (EGFR) signaling modulates the target gene expression profile of GLI transcription factors in epidermal cells. Using expression profili...

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Bibliografiske detaljer
Main Authors: Kasper, Maria, Schnidar, Harald, Neill, Graham W., Hanneder, Michaela, Klingler, Stefan, Blaas, Leander, Schmid, Carmen, Hauser-Kronberger, Cornelia, Regl, Gerhard, Philpott, Michael P., Aberger, Fritz
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592816/
https://ncbi.nlm.nih.gov/pubmed/16880536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02317-05
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