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Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

Hedgehog (HH)/GLI signaling plays a critical role in epidermal development and basal cell carcinoma. Here, we provide evidence that epidermal growth factor receptor (EGFR) signaling modulates the target gene expression profile of GLI transcription factors in epidermal cells. Using expression profili...

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Detalhes bibliográficos
Main Authors: Kasper, Maria, Schnidar, Harald, Neill, Graham W., Hanneder, Michaela, Klingler, Stefan, Blaas, Leander, Schmid, Carmen, Hauser-Kronberger, Cornelia, Regl, Gerhard, Philpott, Michael P., Aberger, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592816/
https://ncbi.nlm.nih.gov/pubmed/16880536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02317-05
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