Hypomorphic Mutation of the TALE Gene Prep1 (pKnox1) Causes a Major Reduction of Pbx and Meis Proteins and a Pleiotropic Embryonic Phenotype

The interaction of Prep1 and Pbx homeodomain transcription factors regulates their activity, nuclear localization, and likely, function in development. To understand the in vivo role of Prep1, we have analyzed an embryonic lethal hypomorphic mutant mouse (Prep1(i)(/)(i)). Prep1(i)(/)(i) embryos die...

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Xehetasun bibliografikoak
Egile Nagusiak: Ferretti, Elisabetta, Villaescusa, J. Carlos, Di Rosa, Patrizia, Fernandez-Diaz, Luis C., Longobardi, Elena, Mazzieri, Roberta, Miccio, Annarita, Micali, Nicola, Selleri, Licia, Ferrari, Giuliana, Blasi, Francesco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592771/
https://ncbi.nlm.nih.gov/pubmed/16847320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00313-06
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