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Spatial Localization of m-Calpain to the Plasma Membrane by Phosphoinositide Biphosphate Binding during Epidermal Growth Factor Receptor-Mediated Activation
Calpain activity is required for de-adhesion of the cell body and rear to enable productive locomotion of adherent cells during wound repair and tumor invasion. Growth factors activate m-calpain (calpain 2, CAPN2) via ERK/mitogen-activated protein kinases, but only when these kinases are localized t...
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Główni autorzy: | , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Microbiology
2006
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592705/ https://ncbi.nlm.nih.gov/pubmed/16809781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02243-05 |
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