Activated Polyamine Catabolism in Acute Pancreatitis : α-Methylated Polyamine Analogues Prevent Trypsinogen Activation and Pancreatitis-Associated Mortality

Polyamines are essential for normal cellular growth and function. Activation of polyamine catabolism in transgenic rats overexpressing spermidine/spermine N(1)-acetyltransferase, the key enzyme in polyamine catabolism, results in severe acute pancreatitis. Here, we investigated the role of polyamine...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Hyvönen, Mervi T., Herzig, Karl-Heinz, Sinervirta, Riitta, Albrecht, Elke, Nordback, Isto, Sand, Juhani, Keinänen, Tuomo A., Vepsäläinen, Jouko, Grigorenko, Nikolay, Khomutov, Alex R., Krüger, Burkhard, Jänne, Juhani, Alhonen, Leena
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2006
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592678/
https://ncbi.nlm.nih.gov/pubmed/16400014
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items