NF-κB2 is required for the establishment of central tolerance through an Aire-dependent pathway

NF-κB2–deficient mice have impaired T and B cell responses. We found, however, that in these mice there was severe infiltration of lymphocytes into multiple organs and increased activity of autoantibodies to peripheral tissue antigens in a manner similar to that of autoimmune regulator–deficient (Ai...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhu, Mingzhao, Chin, Robert K., Christiansen, Peter A., Lo, James C., Liu, Xiaojuan, Ware, Carl, Siebenlist, Ulrich, Fu, Yang-Xin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2006
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592546/
https://ncbi.nlm.nih.gov/pubmed/17039258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28326
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