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NF-κB2 is required for the establishment of central tolerance through an Aire-dependent pathway
NF-κB2–deficient mice have impaired T and B cell responses. We found, however, that in these mice there was severe infiltration of lymphocytes into multiple organs and increased activity of autoantibodies to peripheral tissue antigens in a manner similar to that of autoimmune regulator–deficient (Ai...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592546/ https://ncbi.nlm.nih.gov/pubmed/17039258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28326 |
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