NF-κB2 is required for the establishment of central tolerance through an Aire-dependent pathway

NF-κB2–deficient mice have impaired T and B cell responses. We found, however, that in these mice there was severe infiltration of lymphocytes into multiple organs and increased activity of autoantibodies to peripheral tissue antigens in a manner similar to that of autoimmune regulator–deficient (Ai...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Zhu, Mingzhao, Chin, Robert K., Christiansen, Peter A., Lo, James C., Liu, Xiaojuan, Ware, Carl, Siebenlist, Ulrich, Fu, Yang-Xin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592546/
https://ncbi.nlm.nih.gov/pubmed/17039258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28326
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares