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Crystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1
UPF1 is an essential eukaryotic RNA helicase that plays a key role in various mRNA degradation pathways, notably nonsense-mediated mRNA decay (NMD). In combination with UPF2 and UPF3, it forms part of the surveillance complex that detects mRNAs containing premature stop codons and triggers their deg...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1581972/ https://ncbi.nlm.nih.gov/pubmed/16931876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.177606 |
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