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Rapid vascular regrowth in tumors after reversal of VEGF inhibition

Inhibitors of VEGF signaling can block angiogenesis and reduce tumor vascularity, but little is known about the reversibility of these changes after treatment ends. In the present study, regrowth of blood vessels in spontaneous RIP-Tag2 tumors and implanted Lewis lung carcinomas in mice was assessed...

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Detalhes bibliográficos
Main Authors: Mancuso, Michael R., Davis, Rachel, Norberg, Scott M., O’Brien, Shaun, Sennino, Barbara, Nakahara, Tsutomu, Yao, Virginia J., Inai, Tetsuichiro, Brooks, Peter, Freimark, Bruce, Shalinsky, David R., Hu-Lowe, Dana D., McDonald, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578604/
https://ncbi.nlm.nih.gov/pubmed/17016557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24612
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