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Rapamycin reversal of VEGF-C–driven lymphatic anomalies in the respiratory tract
Lymphatic malformations are serious but poorly understood conditions that present therapeutic challenges. The goal of this study was to compare strategies for inducing regression of abnormal lymphatics and explore underlying mechanisms. CCSP-rtTA/tetO-VEGF-C mice, in which doxycycline regulates VEGF...
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| Veröffentlicht in: | JCI Insight |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621869/ https://ncbi.nlm.nih.gov/pubmed/28814666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90103 |
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