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Rapamycin reversal of VEGF-C–driven lymphatic anomalies in the respiratory tract
Lymphatic malformations are serious but poorly understood conditions that present therapeutic challenges. The goal of this study was to compare strategies for inducing regression of abnormal lymphatics and explore underlying mechanisms. CCSP-rtTA/tetO-VEGF-C mice, in which doxycycline regulates VEGF...
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| Publicado en: | JCI Insight |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5621869/ https://ncbi.nlm.nih.gov/pubmed/28814666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90103 |
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