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Rapamycin reversal of VEGF-C–driven lymphatic anomalies in the respiratory tract

Lymphatic malformations are serious but poorly understood conditions that present therapeutic challenges. The goal of this study was to compare strategies for inducing regression of abnormal lymphatics and explore underlying mechanisms. CCSP-rtTA/tetO-VEGF-C mice, in which doxycycline regulates VEGF...

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Foilsithe in:JCI Insight
Main Authors: Baluk, Peter, Yao, Li-Chin, Flores, Julio C., Choi, Dongwon, Hong, Young-Kwon, McDonald, Donald M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621869/
https://ncbi.nlm.nih.gov/pubmed/28814666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90103
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