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Rapamycin reversal of VEGF-C–driven lymphatic anomalies in the respiratory tract

Lymphatic malformations are serious but poorly understood conditions that present therapeutic challenges. The goal of this study was to compare strategies for inducing regression of abnormal lymphatics and explore underlying mechanisms. CCSP-rtTA/tetO-VEGF-C mice, in which doxycycline regulates VEGF...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Baluk, Peter, Yao, Li-Chin, Flores, Julio C., Choi, Dongwon, Hong, Young-Kwon, McDonald, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621869/
https://ncbi.nlm.nih.gov/pubmed/28814666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90103
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