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Cellular source and amount of VEGF and PDGF in tumors determine response to angiogenesis inhibitors

Vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and their receptors are important targets in cancer therapy based on angiogenesis inhibition. However, it is unclear whether inhibition of VEGF and PDGF together is more effective than inhibition of either one alone. H...

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Podrobná bibliografie
Hlavní autoři: Sennino, Barbara, Kuhnert, Frank, Tabruyn, Sebastien P., Mancuso, Michael R., Hu-Lowe, Dana D., Kuo, Calvin J., McDonald, Donald M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759816/
https://ncbi.nlm.nih.gov/pubmed/19401451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3779
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