Cellular source and amount of VEGF and PDGF in tumors determine response to angiogenesis inhibitors

Vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and their receptors are important targets in cancer therapy based on angiogenesis inhibition. However, it is unclear whether inhibition of VEGF and PDGF together is more effective than inhibition of either one alone. H...

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Main Authors: Sennino, Barbara, Kuhnert, Frank, Tabruyn, Sebastien P., Mancuso, Michael R., Hu-Lowe, Dana D., Kuo, Calvin J., McDonald, Donald M.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759816/
https://ncbi.nlm.nih.gov/pubmed/19401451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3779
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