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Insulin regulation of cholesterol 7α-hydroxylase expression in human hepatocytes: Roles of forkhead box O1 and sterol regulatory element-binding protein 1c*
Bile acid synthesis and pool size increases in diabetes, while insulin inhibits bile acid synthesis. The objective of this study is to elucidate the mechanism of insulin regulation of cholesterol 7α-hydroxylase gene expression in human hepatocytes. Real-time PCR assays showed that physiological conc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576296/ https://ncbi.nlm.nih.gov/pubmed/16885156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M605815200 |
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