Endogenous opioid mechanisms partially mediate P2X(3)/P2X(2/3)-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain

1. P2X(3)/P2X(2/3) receptors have emerged as important components of nociception. However, there is limited information regarding the neurochemical systems that are affected by antagonism of the P2X(3)/P2X(2/3) receptor and that ultimately contribute to the ensuing antinociception. In order to deter...

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Detalhes bibliográficos
Main Authors: McGaraughty, Steve, Honore, Prisca, Wismer, Carol T, Mikusa, Joseph, Zhu, Chang Z, McDonald, Heath A, Bianchi, Bruce, Faltynek, Connie R, Jarvis, Michael F
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576275/
https://ncbi.nlm.nih.gov/pubmed/16041397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706346
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