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Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors

1. Effects of derivatives of coclaurine (C), which mimic the ‘eastern' or the nonquaternary halves of the alkaloids tetrandrine or d-tubocurarine, respectively, both of which are inhibitors of nicotinic acetylcholine receptors (nACh), were examined on recombinant, human α7, α4β2 and α4β4 nACh r...

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Main Authors: Exley, Richard, Iturriaga-Vásquez, Patricio, Lukas, Ronald J, Sher, Emanuele, Cassels, Bruce K, Bermudez, Isabel
格式: Artigo
語言:Inglês
出版: 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576253/
https://ncbi.nlm.nih.gov/pubmed/15980871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706307
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