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Opioid antagonists differ according to negative intrinsic efficacy in a mouse model of acute dependence

1. The purpose of the present study is to compare the capacity of opioid antagonists to elicit withdrawal jumping in mice following two acute pretreatment doses of the opioid agonist morphine. Antagonists that precipitate vigorous withdrawal jumping across both morphine treatment doses are hypothesi...

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Detalles Bibliográficos
Main Authors: Walker, Ellen A, Sterious, Steven N
Formato: Artigo
Idioma:Inglês
Publicado: 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576205/
https://ncbi.nlm.nih.gov/pubmed/15912139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706247
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