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Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.
According to classical models of drug-receptor interactions, competitive antagonists share with agonists the ability to bind to a common site on the receptor molecule. However, they are different from agonists, as they cannot trigger the "stimulus" that leads to biological responses--i.e.,...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1989
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7321 |
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