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Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.

According to classical models of drug-receptor interactions, competitive antagonists share with agonists the ability to bind to a common site on the receptor molecule. However, they are different from agonists, as they cannot trigger the "stimulus" that leads to biological responses--i.e.,...

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Bibliografiske detaljer
Main Authors: Costa, T, Herz, A
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC298053/
https://ncbi.nlm.nih.gov/pubmed/2552439
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