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Stimulus-dependent glucocorticoid-resistance of GM-CSF production in human cultured airway smooth muscle

1. For a subpopulation of asthmatics, symptoms persist even with high doses of glucocorticoids. Glucocorticoids reduce the levels of the proinflammatory and fibrogenic cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF) produced by human cultured airway smooth muscle (ASM). We have c...

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Autors principals: Tran, Thai, Fernandes, Darren J, Schuliga, Michael, Harris, Trudi, Landells, Linda, Stewart, Alastair G
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576125/
https://ncbi.nlm.nih.gov/pubmed/15735656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706174
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