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Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling

BACKGROUND AND PURPOSE: Airway wall remodelling in asthma is characterised by a number of structural changes, including an increase in the volume of airway smooth muscle (ASM), and the abundance of the extracellular matrix (ECM) protein, collagen, is increased. We have investigated the mechanism of...

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Detalhes bibliográficos
Main Authors: Bonacci, J V, Schuliga, M, Harris, T, Stewart, A G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978431/
https://ncbi.nlm.nih.gov/pubmed/16967051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706881
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