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Collagen impairs glucocorticoid actions in airway smooth muscle through integrin signalling

BACKGROUND AND PURPOSE: Airway wall remodelling in asthma is characterised by a number of structural changes, including an increase in the volume of airway smooth muscle (ASM), and the abundance of the extracellular matrix (ECM) protein, collagen, is increased. We have investigated the mechanism of...

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Autores principales: Bonacci, J V, Schuliga, M, Harris, T, Stewart, A G
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978431/
https://ncbi.nlm.nih.gov/pubmed/16967051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706881
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