Llwytho...

Collagen-induced resistance to glucocorticoid anti-mitogenic actions: a potential explanation of smooth muscle hyperplasia in the asthmatic remodelled airway

Glucocorticoids (GCS) inhibit mitogenesis of airway smooth muscle (ASM) cells grown on plastic. We have now evaluated the effects of GCS on proliferation of ASM grown on extracellular matrix proteins (ECM) abundant in noninflamed airways (laminin) and in fibrotic asthmatic airways (collagen type I)....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bonacci, John V, Harris, Trudi, Wilson, John W, Stewart, Alastair G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573763/
https://ncbi.nlm.nih.gov/pubmed/12711618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705135
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