Contribution of the p38(MAPK) signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific

1. We have investigated the role of p38(MAPK) in human airway smooth muscle (HASM) proliferation in response to thrombin and bFGF. The regulation of cyclin D1 mRNA, cyclin D1, cyclin E and p21(Cip1) protein levels, and the extent of retinoblastoma protein (pRb) phosphorylation in response to activat...

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Detalhes bibliográficos
Main Authors: Fernandes, Darren J, Ravenhall, Claire E, Harris, Trudi, Tran, Thai, Vlahos, Ross, Stewart, Alastair G
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575175/
https://ncbi.nlm.nih.gov/pubmed/15249425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705809
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