Contribution of the p38(MAPK) signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific

1. We have investigated the role of p38(MAPK) in human airway smooth muscle (HASM) proliferation in response to thrombin and bFGF. The regulation of cyclin D1 mRNA, cyclin D1, cyclin E and p21(Cip1) protein levels, and the extent of retinoblastoma protein (pRb) phosphorylation in response to activat...

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Hlavní autoři: Fernandes, Darren J, Ravenhall, Claire E, Harris, Trudi, Tran, Thai, Vlahos, Ross, Stewart, Alastair G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575175/
https://ncbi.nlm.nih.gov/pubmed/15249425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705809
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