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Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux

1. Nociceptin/orphanin FQ (N/OFQ) is the endogenous peptide ligand for a specific G-protein coupled receptor, the N/OFQ peptide receptor (NOP). The N/OFQ-NOP receptor system has been reported to play an important role in pain, anxiety and appetite regulation. In airways, N/OFQ was found to inhibit t...

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Bibliographische Detailangaben
Hauptverfasser: D'Agostino, Bruno, Marrocco, Giuseppina, De Nardo, Marilisa, Calò, Girolamo, Guerrini, Remo, Gallelli, Luca, Advenier, Charles, Rossi, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576063/
https://ncbi.nlm.nih.gov/pubmed/15685213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706066
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