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Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury

1. Complement activation is implicated in the pathogenesis of intestinal ischaemia–reperfusion injury (I/R), although the relative importance of individual complement components is unclear. A C3a receptor antagonist N(2)-[(2,2-diphenylethoxy)acetyl]-L-arginine (C3aRA) has been compared with a C5a re...

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Autors principals: Proctor, Lavinia M, Arumugam, Thiruma V, Shiels, Ian, Reid, Robert C, Fairlie, David P, Taylor, Stephen M
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575041/
https://ncbi.nlm.nih.gov/pubmed/15159277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705819
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