Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA(2), COX-1 and COX-2 selective inhibitors, and an LTC(4) receptor antagonist

1. A new group IIa sPLA(2) inhibitor was compared with selective inhibitors of COX-1, COX-2 and an LTC(4) antagonist for effects on local and remote tissue injuries following ischaemia and reperfusion (I/R) of the small intestine in rats. 2. In an acute model of ischaemia (30 min) and reperfusion (1...

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Bibliografiske detaljer
Main Authors: Arumugam, Thiruma V, Arnold, Naomi, Proctor, Lavinia M, Newman, Michelle, Reid, Robert C, Hansford, Karl A, Fairlie, David P, Shiels, Ian A, Taylor, Stephen M
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574000/
https://ncbi.nlm.nih.gov/pubmed/12967936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705402
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