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Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist
1. The relationship of agonist efficacy to the rate of G protein-coupled receptor signaling desensitization is controversial. 2. Expressing inwardly rectifying potassium channels (GIRKs) in Xenopus oocytes, we have devised a signaling assay that clearly identifies CB1 cannabinoid receptor agonists w...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574962/ https://ncbi.nlm.nih.gov/pubmed/15148260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705792 |
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