Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase

Orotidine 5′-monophosphate decarboxylase catalyzes the conversion of orotidine 5′-monophosphate to uridine 5′-monophosphate, the last step in biosynthesis of pyrimidine nucleotides. As part of a Structural Genomics Initiative, the crystal structures of the ligand-free and the6-azauridine 5′-monophos...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Wu, Ning, Mo, Yirong, Gao, Jiali, Pai, Emil F.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2000
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15746/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681441/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050417797
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