Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors

1. Using in vivo intracerebral microdialysis in conscious, freely moving rats, we examined the effect of flibanserin, a potential antidepressant drug with high affinity for human 5-HT(1A) receptors and four–50-fold lower affinity for 5-HT(2A) and D(4) receptors, on basal extracellular concentrations...

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Autors principals: Invernizzi, Roberto William, Sacchetti, Giuseppina, Parini, Stefania, Acconcia, Sabrina, Samanin, Rosario
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573953/
https://ncbi.nlm.nih.gov/pubmed/12890707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705341
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