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Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors
1. Using in vivo intracerebral microdialysis in conscious, freely moving rats, we examined the effect of flibanserin, a potential antidepressant drug with high affinity for human 5-HT(1A) receptors and four–50-fold lower affinity for 5-HT(2A) and D(4) receptors, on basal extracellular concentrations...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573953/ https://ncbi.nlm.nih.gov/pubmed/12890707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705341 |
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