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Studies on the acute and chronic effects of reboxetine on extracellular noradrenaline and other monoamines in the rat brain

1. The effect of reboxetine, a novel antidepressant drug that potently and selectively inhibits neuronal noradrenaline (NA) uptake, on brain extracellular monoamines was studied by microdialysis. 2. Fifteen mg kg(−1) i.p. reboxetine raised extracellular NA in the frontal cortex (by 242%) and dorsal...

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Detalles Bibliográficos
Main Authors: Sacchetti, G, Bernini, M, Bianchetti, A, Parini, S, Invernizzi, R W, Samanin, R
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571760/
https://ncbi.nlm.nih.gov/pubmed/10578149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702926
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